To confirm or reject an order, do following:
Select your order, click on the field "Reject" or "Accept" and set a check mark.

The Vendor Comment field is available and optional when you accept the purchase order.
If you reject the purchase order, it is necessary to specify the reason in the Supplier Comment field.

If you have accepted an order, the status of the order will be changed from NEW PUBLISHED to OPEN.
If you have rejected an order, the status is changed to Rejected.